Oral Lichen Planus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) aged from 18 to 60; (2) Physical examination such as blood pressure, complete blood cell count, hepatic and renal clinical biochemistry, ultrasonic examination of abdomen, chest X-ray, electrocardiogram are normal; (3) Subject decided independently to participate in the study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) serious system diseases; (2) Those with other severe oral mucous diseases; (3) Those taking drugs(beta carotene) during the previous 3 months; (4) Those taking immunopotentiating or immunosuppressive agents during the previous 3 months; (5) Smokier; (6) Pregnancy or intention of pregnancy or lactation or use of contraceptives of steroid hormone recently; (7) People with mental disabilities; (8) Lichenoid disease induced by amalgam or other drugs; (9) People who coming late to an appointment or not following directions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lesion size;the degree keratosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| the pain score;Serum level of lipid peroxide and superoxide dismutase (sod) and glutathione peroxidase (gsh-px) activities; | — |
Countries
China