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Taking beta carotene orally damage to oral squamous moss speckle eliminating effect observation-a randomized controlled multicenter clinical trial

Taking beta carotene orally damage to oral squamous moss speckle eliminating effect observation-a randomized controlled multicenter clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-14005589
Enrollment
Unknown
Registered
2014-12-01
Start date
2014-12-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Lichen Planus

Interventions

A vs B:Taking beta carotene orally

Sponsors

West Chnia hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) aged from 18 to 60; (2) Physical examination such as blood pressure, complete blood cell count, hepatic and renal clinical biochemistry, ultrasonic examination of abdomen, chest X-ray, electrocardiogram are normal; (3) Subject decided independently to participate in the study and sign informed consent.

Exclusion criteria

Exclusion criteria: (1) serious system diseases; (2) Those with other severe oral mucous diseases; (3) Those taking drugs(beta carotene) during the previous 3 months; (4) Those taking immunopotentiating or immunosuppressive agents during the previous 3 months; (5) Smokier; (6) Pregnancy or intention of pregnancy or lactation or use of contraceptives of steroid hormone recently; (7) People with mental disabilities; (8) Lichenoid disease induced by amalgam or other drugs; (9) People who coming late to an appointment or not following directions.

Design outcomes

Primary

MeasureTime frame
lesion size;the degree keratosis;

Secondary

MeasureTime frame
the pain score;Serum level of lipid peroxide and superoxide dismutase (sod) and glutathione peroxidase (gsh-px) activities;

Countries

China

Contacts

Public ContactHongmei Zhou
acomnet@126.com+86 28 85503480

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026