Prehospital Clopidogrel versus Ticagrelor in Patients going Primary Percutaneous Coronary Intervention with Large Anterior Myocardial Infarction on platelet aggregation and myocardial perfusion

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-14005454

Enrollment

Unknown

Registered

2014-11-07

Start date

2014-11-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ST-Segment elevation myocardial infarction

Interventions

A:Clopidogrel 600mg

B:Ticagrelor 180mg

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Men or women are aged 18 to 80; 2. had a symptom duration of more than 30 minutes but less than 6 hours; 3. Electrocardiogram (ecg) of two or more adjacent lead ST segment elevation more than 0.1mV of V1-V4; 4.vAgree to accept direct PCI therapy and agreed to participate in clinical research.

Exclusion criteria

Exclusion criteria: 1. A history of myocardial infarction, CABG or Anterior descending artery stent implantation; 2. Patients were treated with thrombolytic therapy; 3. Having direct PCI contraindications; 4. Having CMR contraindications; 5. Can't stop treatment with oral anticoagulants; 6. Using CYP3A or GP IIb/IIIa Inhibitors; 7. The platelet count less than 100000/mm^3 and more than 700000/mm^3 or Hb less than 100g/L; 8. Having the following conditions: known sick sinus syndrome, second degree atrioventricular block or bradycardia causing syncopeIn the absence of a functional implantable pacemaker case, have any of the following conditions: known sick sinus syndrome, second degree atrioventricular block or bradycardia causing syncope; 9. Within serious infectious diseases;at the end-stage of organic function failureor with advanced cancers and the life expectancy is less than a year; 10. Recent (less than 3 months) had received surgical treatment of patients with traumatic surgery; 11. Patients recently with ischemic stroke, TIA and the history of hemorrhagic stroke (less than 6 months); 12. Participating other clinical trails; 13. Not The proximal left anterior descending artery committed; 14. Going CABG within 30 days; 15. Requiring dialysis or IABP assistant.

Design outcomes

Primary

Measure	Time frame
IPA;TMPG;MSI;	—

Secondary

Measure	Time frame
TIMI;MACE;	—

Contacts

Public ContactDingcheng Xiang

1029181895@qq.com+86 13268265228

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026