bronchiolitis
Conditions
Interventions
control group :support treatement
inhaling 1 group:inhaling combinant human alpha 1b, 1ug/kg
inhaling 2 group:inhaling combinant human alph 1b, 2ug/kg
injection treatment group:inject the interferon alpha 1b
Sponsors
West China Women and Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 2 Years
Inclusion criteria
Inclusion criteria: 1. To be aged 0-24 months; 2. To be diagnosed bronchilitis, with severe Complications or comorbidities, hospitaled; 3. acute phase, course less than 48h.
Exclusion criteria
Exclusion criteria: 1. the severe bronchilitis included:Shock or disturbance of consciousness;Combined with respiratory failure feature; Repeated apnea or appear slow and irregular; 2. adiministration steroids\antivital drugs\immunity regular in 2weeks before hospitalised,or Antiviral Chinese Medicine in 1 week before hospitalised; 3. sensitive to the interferon; 4. children suffering congenital heart disease, liver disease, Kidney and hematopoietic system diseases, Seizures and other central nervous system disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of cyanosis;Breathing level;The degree of cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the peripheral blood of asthma related cytokines;Liver and kidney function;Frequence of asthmatic disease;The frequence of cough occurrence; | — |
Countries
China
Contacts
Public ContactLiu Hanmin
Outcome results
None listed