Effects of sevoflurane on ischemia-reperfusion injury in living donor kidney transplantation

Effects of sevoflurane preconditioning and postconditioning on ischemia-reperfusion injury in living donor kidney transplantation

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-14005399

Enrollment

Unknown

Registered

2014-10-26

Start date

2014-10-30

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic renal failure

Interventions

control group :none

sevoflurane preconditioning group :sevoflurane preconditioning

sevoflurane postconditioning:sevoflurane postconditioning

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 years and scheduled for living donor kidney transplantation were eligible for the study.

Exclusion criteria

Exclusion criteria: Patients were excluded from the study if they were Younger than 18 years, underwent emergency surgery, had the history of organ transplant, taken immunosuppressant drugs or suffered from diabetes and severe peripheral vascular disease.

Design outcomes

Primary

Measure	Time frame
urine volume;postoperative complications;serum creatinine;blood urea nitrogen;CysC;eGFR;NGAL;Histological analysis of kidney;IL-1 beta;IL-10;TNF-alpha;IL-2;IFN-gama;Mononuclear cells;Activated T cell ratio;caspase-1;NLRP3;	—

Countries

China

Contacts

Public ContactXiaoxia An

anxxls@163.com+86 13858180512

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026