chronic cholecystitis (liver-gallbladder dampness-heat syndrome)
Conditions
Interventions
high dosage group:high dosage of Jin-yin-li-dan granules
middle dosage group:middle dosage of Jin-yin-li-dan granules
low dosage group:low dosage of Jin-yin-li-dan granules
placebo group :placebo of Jin-yin-li-dan granules
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged between 18 to 65 years with a confirmed diagnosis of chronic cholecystitis (liver-gallbladder dampness-heat syndrome) and informed consent was obtained from all patients or their legal representatives prior to randomization.
Exclusion criteria
Exclusion criteria: (1) acute cholecystitis including simple, purulent and gangrenous cholecystitis;biliary obstructive disease, acute obstructive suppurative cholangitis, gallbladder perforation complicated with diffuse peritonitis; (2) T heigher than 37.5 degree, WBC more than 11*10^9/L, Neu more than 80%; (3) With the intention of pregnant, pregnant or lactating women; (4) With the intention of surgery in 4 months; (5) With severe primary diseases of the heart, liver, kidney, blood system and endocrinium, such as tumour or AIDS; diabetes; psychotics; abnormal renal function (Scr); urine protein more than positive; AST, ALT more than 1.5 times of the high normal range; abnormal ECG; WBC less than 3.0*10^9/L; (6) Patients participated in other clinical trials within three months; (7) Allergic constitution or allergic to this drug or to the known composition of placebo; (8) Patients are doubt or do have the abuse history of alcohol or drug; (9) Poor compliant patients; (10) Patients with disabilities (blind, deaf, dumb, dysgnosia, dysphrenia, physical disabilities).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS of main symptom;cumulative traditional Chinese medicine syndrome score;colour doppler ultrasound efficacy;recurrence rate and frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| security evaluation indexes; | — |
Countries
China
Contacts
Public ContactXiao-Nan Yang
Outcome results
None listed