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Evaluation of Efficacy and Safety of Binglian Qingyan spray for Acute Pharyngitis or Acute attack of Chronic Pharyngitis: A Multicenter, Randomized, Blinding, Parallel Active-Controlled Trial

Evaluation of Efficacy and Safety of Binglian Qingyan spray for Acute Pharyngitis or Acute attack of Chronic Pharyngitis: A Multicenter, Randomized, Blinding, Parallel Active-Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-14005356
Enrollment
Unknown
Registered
2014-08-06
Start date
2014-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pharyngitis or Acute attack of Chronic Pharyngitis

Interventions

experiment group:Binglian Qingyan
control group 1:Jinsangzi
control group 2:Jinhoujian

Sponsors

Wuhan Union Hospital, Tongji Medical college, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Conform to the western medicine of acute pharyngitis or acute attack of chronic pharyngitis disease diagnostic criteria; (2) Acute onset, course of primary-care within 72 hours; (3) Male or female subjects aged 18-65; (4) No drug intervention or other treatment associated with acute pharyngitis or acute attack of chronic pharyngitis; (5) Voluntarily signed the informed consent and having good adherence.

Exclusion criteria

Exclusion criteria: (1) Patients with measles, scarlet fever, flu, agranulocytosis, infectious mononucleosis, such as leukemia, acute carotid inflammation caused by pharyngeal symptoms or inflammation; (2) Temperature higher than 38.5 degree; Blood WBC more than 10*10^9/L, or with pneumonia and bronchitis; Suppurative tonsillitis; (3) Pregnant or lactating women; (4) Patients with serious heart, brain, lung, liver, kidney disease, blood disease, or seriously affect the survival of the disease, such as cancer or AIDS; (5) ALT above 2 times more than normal reference range; (6) Allergic to the trial medicine; (7) Patients with disability according to the law (blind, deaf, mental retardation, mental disorder, physical disabilities, etc.); (8) Patients with history of having alcohol or drug abuse, or according to the judgment of the researchers, have lower possibility into the group or complicate the group's other lesions, such as working environment changeing frequently to cause lost to follow-up; (9) Patients were enrolled in other trial within last month; (10) Patients are taking part in other trial.

Design outcomes

Primary

MeasureTime frame
sore throat;pharyngeal mucosa irritation;uvula irritation;

Secondary

MeasureTime frame
Other individual symptoms;physical signs of efficacy;

Countries

China

Contacts

Public ContactWeijia Kong
wjkong@whuh.com+86 027-85351632

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026