Plasma BDNF correlates with emergence agitation and cognitive decline in the elders

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-14005292

Enrollment

Unknown

Registered

2014-08-27

Start date

2013-02-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

emergence agitation and cognitive decline

Interventions

Two groups:general anesthesia

Eligibility

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 50-75 years old in patients undergoing abdominal secondary surgery, ASA classification Grade I, II.

Exclusion criteria

Exclusion criteria: 1. The patient god classics disease or mental illness; 2. Patients with renal insufficiency, serum creatinine more than tendency for 177/L; 3. Patients with active liver disease; 4. Patients with serious cardiovascular diseases; 5. The patients with pulmonary dysfunction; 6. Patients with endocrine diseases; 7. Patients with metabolic disease; 8 patients with a history of surgery; 9. Patients with MMSE score less than 24; 10. Patients can not finish the neuropsychological tests; 11. Patients with visual impairment; 12. Patients with hearing impairment, or can't understand mandarin Chinese; 13. Patients allergic to propofol or other narcotic ingredients; 14. Plan or to perform the test.

Design outcomes

Primary

Measure	Time frame
brain-derived neurotrophic factor;emergence agitation;	—

Countries

China

Contacts

Public ContactMei Xi

705406446@qq.com+86 15873162864

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026