Mild Cognitive Impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Both the following 5 items are required: (1) Cognitive impairment; (2) Normal Activities of Daily Living; (3) Without dementia; (4) Aged between 50 to 80 years; (5) The patient or their legal representative signed the informed consent.
Exclusion criteria
Exclusion criteria: Subjects will be excluded when complied any of the item following: (1) Transient ischemic attack (TIA); (2) Cerebral hemorrhage or subarachnoid hemorrhage; (3) Check confirmed that the stroke was caused by brain tumors,brain trauma and blood diseases; (4) Cerebral embolism caused by atrial fibrillation with rheumatic heart disease, coronary heart disease or any other heart diseases; (5) Bone and joint diseases and some other serious diseases which were associated with liver, kidney, hematopoietic system and endocrine system etc.; (6) Mental disorders or severe dementia; (7) Patients can not be performed with MRI which has accepted pacemaker surgery, coronary intervention surgery or coronary artery bypass surgery; (8) Patients can not be performed with MRI which has a magnetic implant inside.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination (MMSE);Auditory Verbal Learning Test (AVLT);Montreal cognitive assessment (MoCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Boston Naming Test (BNT);Symbol Digit Modalities Test (SDMT);Digit Span Test;Clock Drawing Test (CDT);Stroop Color-word Test;Trail Making Test (TMT);Activity of Daily living (ADL); | — |
Countries
China