osteoarthritis
Conditions
Interventions
Moderate Dose Group :10mg/kg dose of tranexamic acid
High Dose Group:15mg/kg dose of tranexamic acid
Sponsors
Shanghai Changzheng Hospital
Eligibility
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: (1) To be aged older than 18; (2) patients with DDH and/or OA on hip joint; (3) patients undergoing selective operation of cementless total hip arthroplasty; (4) patients who have signed informed consent.
Exclusion criteria
Exclusion criteria: (1) To be aged older than 80; (2) patients with a history of deep vein thrombosis or embolism; (3) patients with a history of drug sensitivity; (4) patients with anemia; (5) patients with a history of coagulopathy or thrombocytopenia; (6) patients with a history of hepatic or renal failure as well as severe chronic heart failure; (7) patients with a history of neurological or cerebrovascular disease; (8) patients with a history of well as those with a hip surgery previously; (9) patients with other reasons that should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative blood loss;Hb reduction of day 1;Actual blood loss;Post-operative blood loss;Transfusion volume;Hb reduction on day 5; | — |
Secondary
| Measure | Time frame |
|---|---|
| operating time; | — |
Countries
China
Contacts
Public ContactFu Peiliang
Outcome results
None listed