Effects of glucocorticoid on changes of pulmonary function and serum cortisol during rheumatic valve replacemental perioperation

Effects of glucocorticoid on Changes of pulmonary function and serum cortisol during rheumatic valve replacemental perioperation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPQ-16008781

Enrollment

Unknown

Registered

2016-07-04

Start date

2016-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatic heart valve disease

Interventions

Group A:Dexamethasone

Group B:Placebo

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients were diagnosed as rheumatic heart disease, and there were indications for bypass valve replacement. All patients voluntarily joined in the study.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Patients with hypertension, peptic ulcer disease, mental disease, glaucoma, hypercortisolism, diabetes, hyperthyroidism and hyperthyroidism or thyroid dysfunctionendocrine or other endocrine disease. and the patients used glucocorticoids before operation in one month.

Design outcomes

Primary

Measure	Time frame
Peak expiratory flow;plasma cortisol concentration;24-hour urinary cortisol;	—

Countries

China

Contacts

Public ContactJiang Ying-jiu

Department of Cardiothoracic Surgery of the First Affiliated Hospital of Chongqing Medical University

jiangyinjiu@aliyun.com+86 13101348339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026