Evaluation of non-depolarizing muscle relaxants on intraocular pressure in patients with normal intraocular pressure and high intraocular pressure
Conditions
Interventions
glaucoma group:given rocuronium0.9mg/kg
glaucoma group:given rocuronium0.6mg/kg
non-glaucoma group:given rocuronium0.9mg/kg
non-glaucoma group:given rocuronium0.6mg/kg
glaucoma group:given cisatracurium0.1mg/kg
non-glaucoma group:given cisatracurium0.1mg/kg
glaucoma group:given cisatracurium0.15mg/kg
non-glaucoma group:given cisatracurium0.15mg/kg
glaucoma group:given cisatracurium0.2mg/kg
non-glaucoma group:given cisatracurium0.2mg/kg
Sponsors
The Eye, Ear, Nose and Throat Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ASA physical status I and II patients scheduled for ophthalmic surgery, of either gender, between the ages of 18 and 65 years
Exclusion criteria
Exclusion criteria: ocular trauma, pregnacy, neuromuscular disorders, receiving medicine known to interfere with neuromuscular function, allergy to the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraocular pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| systolic pressure;diastolic pressure;Mean pressure;heart rate;Pulse oxygen saturation;the value of train of four stimulation;Spontaneous breathing recovery time;awake time;time of removing the laryngeal mask;Recovery time of muscle relaxation; | — |
Countries
China
Contacts
Public ContactFang Tan
The Eye, Ear, Nose and Throat Hospital, Fudan University
Outcome results
None listed