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ED50 and ED95 of prophylactic infusion of phenylephrine to prevent post-spinal hypotension in cesarean section: a prospective study.

ED50 and ED95 of prophylactic infusion of phenylephrine to prevent post-spinal hypotension in cesarean section: a prospective study.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPD-17011526
Enrollment
Unknown
Registered
2017-05-31
Start date
2017-06-01
Completion date
Unknown
Last updated
2017-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypotension

Interventions

0.25:0.25mcg/kg/min prophylactic infusion of phenylephrine
0.375:0.375mcg/kg/min prophylactic infusion of phenylephrine
0.5:0.5mcg/kg/min prophylactic infusion of phenylephrine
0.625:0.625mcg/kg/min ???????????

Sponsors

Jiaxing University Affiliated Women and Children Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical class I or II, scheduled for elective ceasarean delivery, were enrolled in this study.

Exclusion criteria

Exclusion criteria: Patients with obesity (body mass index (BMI) > 35 kg/m2), gestational age < 37 weeks, active labor, early labor, ruptured membranes, history of previous cesarean deliveries, diabetes or gestational diabetes, hypertension or pre-eclampsia, intrauterine growth restriction, placenta previa, significant coexisting maternal disease, any contraindication to spinal or epidural anesthesia such as local infection or bleeding disorders.

Design outcomes

Primary

MeasureTime frame
effective or ineffective of prophylactic phenylephrine in prevention of spinal induced hypotension;

Secondary

MeasureTime frame
side effects;maternal hemodynamics;

Countries

China

Contacts

Public ContactFei Xiao

Jiaxing University Affiliated Women and Children Hospital

13706597501@163.com+86 13706597501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026