NGAL, KIM-1 and IL-18 for Prediction of the outcome in the patients with contrast-induced acute kidney injury and the reassessment of statins intervention

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPD-17010596

Enrollment

Unknown

Registered

2017-02-09

Start date

2015-07-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

contrast-induced acute kidney injury

Interventions

A group:Intensive treatment with atorvastatin

B group:Conventional treatment with atorvastatin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. the patients underwent coronary angiography in Department of Cardiology, Ningbo No. 2 Hospital, aged> 18 years old; 2. All patients were treated with low-osmolar non-ionic contrast agent ((Iohexol), the amount of 100-450ml.

Exclusion criteria

Exclusion criteria: 1. renal function fluctuates more than 20% of the baseline 1 month before angiography; 2. iodine contrast agent or statin allergy,the patients who have been taking statins before surgery; 3. acute and chronic infection; 4. Acute renal failure, CKD stage 4 and 5, peritoneal dialysis, or hemodialysis; 5. Malignancies, autoimmune diseases; 6. Patients who have undergone a contrast agent test in the last week; 7. No wish to join the study and any other involved in another relevant research; 8. Patients with poor compliance; 9. Severe heart failure, severe arrhythmia.

Design outcomes

Primary

Measure	Time frame
Neutrophil gelatinase-associated lipocalin;Kidney injury molecule-1;Interleukin 18;serum creatinine;	—

Countries

china

Contacts

Public ContactHonghua Ye

Ningbo 2nd Hospital

961430454@qq.com+86 17855848090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026