Psoriasis
Conditions
Interventions
Two groups:A topical application containing Radix Rubiae twice a day for 12 weeks versus A vehicle preparation on other side of the psoriatic lesion
Sponsors
School of Chinese Medicine, CUHK
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Men or women aged between 18 and 75 years old; 2. Mild to moderate, bilateral symmetric, chronic plaque psoriasis; and 3. In good general health, as evidenced by blood, liver and renal function tests conducted prior to the commencement of the study.
Exclusion criteria
Exclusion criteria: 1. Chronic plaque psoriasis involving >80% of the body surface; 2. Pustular or generalized erythrodermic psoriasis; 3. Systemic therapy for psoriasis within 30 d of baseline; 4. Use topical medications for psoriasis within 14 d of baseline such as retinoids, corticosteroids, vitamin D analogues, tazarotene and tacrolimus; 5. UV light therapy within 30 d of baseline; 6. Clinically significant laboratory abnormality in blood, liver or renal functions; 7. A history of sensitive to Chinese herbs or petroleum jelly; 8. Unwillingness to comply with study protocol; and 9. Any other condition that in the opinion of the investigators could compromise the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PASI scores (area involved, erythema, induration and scaling scores) on the baseline and weeks 6 and 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| Impact of Psoriasis Questionnaire (IPSO) on baseline and weeks 12;SF36 on the baseline and weeks 12; | — |
Countries
China
Contacts
Public ContactLIN Zhi-Xiu
Outcome results
None listed