Randomized study comparing arthroscopic debridement and two-stage total joint arthroplasty in patient with septic degenerative joint

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPC-15006943

Enrollment

Unknown

Registered

2015-08-20

Start date

2015-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

septic degenerative joint

Interventions

Two groups:To compare the effectiveness of two-stage total joint arthroplasty to the current standard management method - arthroscopic debridement or open arthrotomy washout

Eligibility

Sex/Gender

All

Age

40 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria are patients with the following conditions: 1. aged 40 or above; 2. history of knee/hip arthritis pain prior to the development of septic arthritis; 3. Positive microbiology culture; 4. Radiographic evident of OA with a KL grade of III/IV; 5. Evident of subchondral erosion of >2mm; 6. Evident of avascular necrosis.

Exclusion criteria

Exclusion criteria: The following patients will be excluded: 1. Patient who are medically not fit for surgery; 2. Patient who are non-ambulatory; 3. Impaired cognitive function; 4.Unable to comply with the rehabilitation.

Design outcomes

Primary

Measure	Time frame
Functional performance will be assessed by KSS, HHS, VAS and WOMAC;Laboratory test;Microbiology test;Radiological examination and SF-36;Physical examination;	—

Secondary

Measure	Time frame
recurrence rate of infection;number of operation done (re-revision for infection),;complications of surgery (aseptic prosthesis loosening, spacer integrity and stability);length of stay in hospital;	—

Countries

China

Contacts

Public ContactProf. Kevin HO Ki Wai

kevinho@cuhk.edu.hk+852 26322715

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026