Effect of combining dexmedetomidine and tramadol for analgesia after simple nephrectomy

Effect of combining dexmedetomidine and tramadol for postoperative analgesia: A double-blinded, randomized trial after simple nephrectomy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPC-14005418

Enrollment

Unknown

Registered

2014-10-28

Start date

2014-11-17

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

analgesia

Interventions

1:tramadol

2:dexmedetomidine combined with tramadol

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patients undergoing elective simple nephrectomy and general anesthesia, to be aged 18 to 65 years, ASA I-III, observing time in PACU longer than 30 min after general anesthesia and no history of mental illness were studied.

Exclusion criteria

Exclusion criteria: The following criteria were used to exclude patients from this study: younger than 18 years, pregnancy or lactation, brain surgery, history of mental disorders, use of psychotropic drugs within 6 months prior to surgery, severe allergies, PACU stay after general anesthesia shorter than 30 min, or reliance on a ventilator due to serious system or organ failure, local anaestheisa, peripheral nerve blocks and epidural anesthesia.

Design outcomes

Primary

Measure	Time frame
SpO2;HR;blood pressure;agitation scores;analgesic scores;sedation scores;The tramadol consumption;degree of satisfaction with analgesia;sleep quality scores;Respiratory rate;PONV;Dizzy;	—

Countries

China

Contacts

Public ContactZhou Jin

zhoujin6@126.com+86 13309881913

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026