Immune thrombocytopenia
Conditions
Interventions
Group 1:Siwu Ejiao Decoction
Group 1:Sijunzi decoction plus Siwu Ejiao Decoction
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the ITP diagnostic criteria, duration = 3 months; 2. The average platelet count =10×10^9/L in 2 weeks; 3. aged between 18 to 75 years old male and female; 4. did not participate in other clinical studies, voluntary in this study.
Exclusion criteria
Exclusion criteria: 1. Severe gastrointestinal bleeding (poor control), or (and) organ bleeding; 2. More than 2 subcutaneous mucosal bleeding or ecchymosis; 3. Subjects used other drugs other than ITP, such as IVIG, CTX, VCR, rTPO, IL-11, rituximab and elquipep, within 14 days before entering the trial. 4. does not meet the criteria for inclusion in clinical research programs; 5. organ insufficiency: serum creatinine greater than the upper limit of normal; alanine aminotransferase, aspartate transaminase, bilirubin greater than 2 times the upper limit of normal; NYHA classification = ? level; 6. Pregnancy, lactating women, allergies; 7. To participate in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| immune cells: CD4+ CD25+ CD127low T cells; CD19+ CD24+ CD27+ (or CD19+ CD24+ CD38hi); CD19 + IL-10+; Th17: CD4+ CD17+ IFN; Th1, Th2; | — |
Contacts
Public ContactHu Xiaomei
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed