stable coronary artery disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 35 to 79 years; 2. Compliance with diagnostic criteria of stable coronary heart disease; 3. Classification of CCS cardiac function beween I-III; 4. Submitted informed consent.
Exclusion criteria
Exclusion criteria: 1. Left main coronary artery stenosis; 2. Uncontrolled hypertension or systolic pressure=160mmHg and/or diastolic pressure=100mmHg after taken medicine; 3. Uncontrolled rapid arrhythmias with symptoms or hemodynamic disorders; 4. High or complete atrioventricular block; 5. acute endocarditis; 6. Obstructive hypertrophic cardiomyopathy; 7. Symptomatic severe aortic stenosis, decompensated heart failure, acute pulmonary embolism, deep vein thrombosis, acute pericarditis, myocarditis and acute aortic dissection; 8. Chronic pulmonary disease with dyspnea; 9. Stroke or transient ischemic attack with cognitive impairment in the short term; 10. The clinical problems that have not been corrected, such as infection, severe anemia, electrolyte disorder, hyperthyroidism, etc; 11. The abnormal function of liver and kidney (serum alanine aminotransferase or creatinine > 2 times the upper limit of normal reference value); 12. Unable to exercise due to limb disorders or other reasons; 13. Patients who are included in other clinical trials in the recent 1 months; 14. Other situations that researchers considered not suitable for the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiopulmonary exercise test: oxygen uptake (VO2), metabolic equivalent, O2 Pulse, Exercise load (watt), Exercise time, Hate rate, etc;Syndrome scoring table of Traditional Chinese Medicine;Four items of blood lipid (TC, TG, LDL-C, HDL-C); | — |
Secondary
| Measure | Time frame |
|---|---|
| The integral of angina pectoris;Five-level Euro Qol five-dimen sional questionnaire (EQ-5D-5L);General Hospital Anxiety and Depression scale (HAD);High sensitive C-reactive protein (hs-crp);Composite end point (all causes of death, acute coronary syndrome, blood revascularization, heart failure, malignant arrhythmia, cardiogenic shock, stroke, pulmonary embolism, etc); | — |
Countries
China
Contacts
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine