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Dexmedetomidine Added to Ropivacaine in Ultrasound-guided Tranversus Abdominis Plane Block Improved Postoperative Analgesia and Recovery after Laparoscopic Radical Operation on Colon

Dexmedetomidine Added to Ropivacaine in Ultrasound-guided Tranversus Abdominis Plane Block Improved Postoperative Analgesia and Recovery after Laparoscopic Radical Operation on Colon

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17014122
Enrollment
Unknown
Registered
2017-12-24
Start date
2017-12-30
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colon cancer

Interventions

study group:TAP with 20 mL of ropivacaine 0.375% plus 2mL of DEX (1µg/kg)
control group:TAP with 20 mL of ropivacaine 0.375% plus 2mL normal saline

Sponsors

The Affiliated Yantai Yuhuangding Hospital of Qingdao Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: 70 ASA I-II patients (aged 25-65 years, weighted 52-83 kg) scheduled for laparoscopic radical operation on colon under general anaesthesia were registered.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had a history of allergy to the drugs used in this study, psychological disorders, infection of the block injection site or any other contraindications for TAPB, tolerance to opioids or if they had used opioids within 48 h prior to the study.

Design outcomes

Primary

MeasureTime frame
resting VAS pain score;VAS score after exercise;

Secondary

MeasureTime frame
The highest level of sensory block;duration of sensory block;the duration of analgesia;sedation score;

Countries

China

Contacts

Public ContactMa Jiahai

The Affiliated Yantai Yuhuangding Hospital of Qingdao Medical College

mjh-214@126.com+86 13656456186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026