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Oral corticosteroids treatment in patients with acute exacerbation of chronic obstructive pulmonary disease

Oral corticosteroids in patients with acute exacerbation of chronic obstructive pulmonary disease.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013847
Enrollment
Unknown
Registered
2017-12-11
Start date
2018-03-01
Completion date
Unknown
Last updated
2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

1:prednisone40mg*5d
2:prednisone*10d

Sponsors

Tianjin First Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Lung function:FEVJFVC<70%, or FEVl<80%ofthe predicted value; 2. Have symptoms of the following three clinical findings: worsening of dyspnea; increase in sputum purulence; and increase in sputum volume.

Exclusion criteria

Exclusion criteria: 1. History of asthma and allergic disease; 2. Bronchodilators test positive; 3. Use of systemic steroids within one month; 4. Respiratory failure requires mechanical ventilation; 5. Combined with pneumonia, pneumothorax, heart failure, severe arrhythmias, pneumothorax, pleural effusion, thromboembolism, endocrine disease; 6. Combined with severe organ dysfunction or malignant tumor; 7. Patients who still smoke; 8. History of mental illness, alcohol or drug abuse; 9. Refuse to cooperate.

Design outcomes

Primary

MeasureTime frame
pulmonary function;—

Secondary

MeasureTime frame
CAT score improvement;—

Countries

China

Contacts

Public ContactRongfei Sun

Tianjin First Center Hospital

srf013@163.com+86 18502221998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026