postoperative cognitive dysfunction
Conditions
Interventions
Group 1:fraction of inspired oxygen 30%
Group 2:fraction of inspired oxygen 60%
Group 3:fraction of inspired oxygen 80%
Sponsors
The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Voluntary participation in the study and signed informed consent,elderly patients over the age of 60 with general anesthesia and thoracic or lumbar prone surgery, the estimated operation time> 2 hours; ASA grade I-III patients; no upper respiratory infection within 1 month, no cardiovascular and cerebrovascular accident within 6 months
Exclusion criteria
Exclusion criteria: Disorders of consciousness, elderly patients with severe cognitive impairment; patients with severe arrhythmia and malignant hypertension; serious cardiovascular and cerebrovascular disease patients with hemiplegia, speech negative, audio-visual dysfunction; Serious arrhythmia, liver and kidney dysfunction, and patients with other severe systemic diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative cognitive score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heat Reat;Pulse Oxygen Saturation;artery blood gas analytica;cerebral oxygen saturation; | — |
Countries
China
Contacts
Public ContactXuefei Ye
The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
Outcome results
None listed