Skip to content

Huanglian Decoction in the treatment of spleen deficiency and damp-heat type Hp positive chronic gastritis: a randomized controlled trial

Huanglian Decoction in the treatment of spleen deficiency and damp-heat type Hp positive chronic gastritis: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013690
Enrollment
Unknown
Registered
2017-12-05
Start date
2018-03-01
Completion date
Unknown
Last updated
2017-12-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic gastritis

Interventions

The Treatment Group:Huanglian Decoction
The Control Group:PPI triple therapy

Sponsors

Tianjin First Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. accord with diagnostic criteria for chronic gastritis; 2. The detection methods of more than two different principles confirmed HP positive(Stop using PPI, H2RA, bismuth, and antibiotics for the first two weeks of examination); 3. Aged between 20~80 years; 4. Permanent local, informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Chronic atrophic gastritis with severe dysplasiaUpper gastrointestinal bleedingPeptic ulcerGastrointestinal tumor; 2. Organic pathological changes of digestive system(chronic pancreatitisCirrhosis etc.), or systemic disease that has an influence on the power of the alimentary tract (Hyperthyroidism, diabetes, chronic renal insufficiency, mental and nervous system lesions etc.); 3. Patients with major organ diseases such as heart and liver, kidney and other major organs, hematopoietic system diseases, and tumors; 4. Use of drugs that may affect the results of the test within 2 weeks (Acid resistant, PPI, H2RA, bismuth and antibiotics); 5. HP had been eradicated in 1 years but failed; 6. Pregnant women and breast-feeding women; 7. There is a history of allergy to the drug research institute.

Design outcomes

Primary

MeasureTime frame
Chronic gastritis symptom checklist;C13 urea breath test;

Countries

China

Contacts

Public ContactNawen Liu

Tianjin First Center Hospital

nn1747@sina.com+86 18920019070

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026