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Comparison of renal injury in children with liver transplantation under combined anesthesia with sevoflurane and propofol

The influence of sevoflurane and propofol on acute kidney injury in pediatric living donor liver transplantion

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013585
Enrollment
Unknown
Registered
2017-11-24
Start date
2018-06-14
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital biliary atresia

Interventions

P:Propofol compound anesthesia
Se:Sevoflurane compound anesthesia

Sponsors

Tianjin First Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
0.5 Years to 2 Years

Inclusion criteria

Inclusion criteria: (1) the classification of anaesthesia (ASA grade) III to IV; (2) Cardiac function grade I to III;

Exclusion criteria

Exclusion criteria: (1) Repeate liver transplantation; (2) patients complicated with heart, lung and kidney failure; (3) Complicated with congenital heart disease.

Design outcomes

Primary

MeasureTime frame
the incidence of AKI;Scr;BUN;IL-10;IL-18;NGAL;TNF-a;SOD;MDA;H2O2;—

Secondary

MeasureTime frame
MAP;HR;CVP;extubation time;ICU time;hospitalization;—

Countries

China

Contacts

Public ContactYu Wenli

Tianjin First Central Hospital

yzxyuwenli@163.com+86 13920098326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026