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Clinical outcomes of Volatile anesthesia versus total IV anesthesia in caRdiac Surgery Trial (VIRS): A multicenter randomized controlled trial

Clinical outcomes of Volatile anesthesia versus total IV anesthesia in caRdiac Surgery Trial (VIRS): A multicenter randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013578
Enrollment
Unknown
Registered
2017-11-28
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac surgery

Interventions

the volatile group:received sevoflurane or desflurane during surgery
the TIVA group:received any intravenous agent and no volatile agent during surgery

Sponsors

Department of Anesthesiology, West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. aged older than 18 years; 2. elective cardiac surgery; 3. signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Minimally invasive cardiac surgery (e.g. transthoracic atrial or ventricular septal defect closure, pericardiectomy); 2. emergency surgery; 3. pregnancy; 4. suspected family history of malignant hyperthermia or propofol infusion syndrome; 5. failed to cooperate with follow-up because of disturbance of comprehension.

Design outcomes

Primary

MeasureTime frame
a composite of major complications and death from any cause occurring within the first 30 days;

Secondary

MeasureTime frame
mortality from any cause at 6-month and at one year;quality of life at one year (SF-8);postoperative mechanical ventilation time;the length of stay in intensive care unit;the length of stay in hospital;total hospital cost;

Countries

China

Contacts

Public ContactJin Liu

Department of Anesthesiology, West China Hospital of Sichuan University

scujinliu@foxmail.com+86 18980601539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026