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A perspective randomized control sduty to evaluate the effect of local 'cocktail' injection for pain and bleeding control after posterior spinal operation

A perspective randomized control sduty to evaluate the effect of local 'cocktail' injection for pain and bleeding control after posterior spinal operation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013385
Enrollment
Unknown
Registered
2017-11-14
Start date
2017-12-04
Completion date
Unknown
Last updated
2017-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar degenerative disease

Interventions

experimental group:Local injection around incision "cocktail" around the incision
control group:Analgesia pump was used after operation

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Aged between 18-80 year; 2) The diagnosis is a lumbar degenerative disease such as lumbar vertebral disc herniation, lumbar spondylosis or lumbar vertebral canal stenosis; 3) Surgical methods is decompression, bone grafting and fixation; 4) Surgical incision is the median incision in the low back; 5) The patient had normal mental behavior; 6) Patients with no serious cerebral and vascular disease that can not under general anesthesia.;Inclusion criteria: 1) Aged between 18-80 year; 2) The diagnosis is a lumbar degenerative disease such as lumbar vertebral disc herniation, lumbar spondylosis or lumbar vertebral canal stenosis; 3) Surgical methods is decompression, bone grafting and fixation; 4) Surgical incision is the median incision in the low back; 5) The patient had normal mental behavior; 6) Patients with no serious cerebral and vascular disease that can not under general anesthesia.

Exclusion criteria

Exclusion criteria: 1) Patients with lumbar tumor, tuberculosis, infection and lumbar vertebral fracture caused by trauma; 2) Patients with abnormal mental behavior; 3) Patients with severe cardiovascular disease that can not tolerate general anesthesia; 4) Patients who have undergone lumbar surgery in the past; 5) Allergic to any drug in the cocktail recipe.;Exclusion criteria: 1) Patients with lumbar tumor, tuberculosis, infection and lumbar vertebral fracture caused by trauma; 2) Patients with abnormal mental behavior; 3) Patients with severe cardiovascular disease that can not tolerate general anesthesia; 4) Patients who have undergone lumbar surgery in the past; 5) Allergic to any drug in the cocktail recipe.

Design outcomes

Primary

MeasureTime frame
VAS;JOA;hemoglobin;albumin;ESR;CRP;IL-1;IL-6;IL-6;TNF-a;;VAS;JOA;hemoglobin;albumin;ESR;CRP;IL-1;IL-6;IL-6;TNF-a;

Countries

China

Contacts

Public ContactJIE HAO;JIE HAO ;

The First Affiliated Hospital of Chongqing Medical University;The First Affiliated Hospital of Chongqing Medical University

spinehao@163.com;spinehao@163.com+86 13996120738;+86 13996120738

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026