Helicobacter pylori infection
Conditions
Interventions
group A:losec-clarithromycin-amoxicillin therapy of 10-day
group A:losec-clarithromycin-amoxicillin therapy of 14-day
group C:losec-berberine-amoxicillin therapy of 10-day
group D:losec-berberine-amoxicillin therapy of 14-day
Sponsors
Guangzhou Wemen and Children's Medical Center
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. No antibiotics, PPI, H2 receptor antagonists, NASAIDs and other drugs within one month before endoscopy; 2. No allergies to the drug used in the study; 3. No acute gastrointestinal bleeding obstruction; Circulation, respiratory, urinary, neurological, blood system diseases, no endocrine, genetic metabolism and other systemic diseases; 4. Endoscopic diagnosis of chronic superficial gastritis; 5. meet the diagnostic criteria for Hp infection.
Exclusion criteria
Exclusion criteria: 1. poor follow up; 2. gastrointestinal ulcers and bleeding; 3. can not tolerate adverse reactions; 4. other diseases happen during the treatment; 5. G6PD dificient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| GI symtom;cost; | — |
Countries
China
Contacts
Public ContactZhaohui Xu
Guangzhou Wemen and Children's Medical Center
Outcome results
None listed