Skip to content

Effect of general anesthesia combined with epidural anesthesia on the immune system function of patient undergoing laparoscopic radical resection for malignant tumor

Effect of general anesthesia combined with epidural anesthesia on the immune system function of patient undergoing laparoscopic radical resection for malignant tumor

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013300
Enrollment
Unknown
Registered
2017-11-08
Start date
2018-01-01
Completion date
Unknown
Last updated
2017-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tumor immunology

Interventions

group of Inhalation anesthesia:total inhalation anesthesia
group of total intravenous anesthesia:total intravenous anesthesia
group of epidural combined with intravenous anesthesia:epidural combined with intravenous anesthesia
group of the lateral nerve block combined with intravenous anesthesia:The lateral nerve block combined with intravenous anesthesia

Sponsors

Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: The inclusion criterion of the clinical trial was elderly patients (65–85 years, ASA: II or III) scheduled for laparoscopic abdominal tumor surgery, including pancreaticoduodenectomy or radical cystectomy.

Exclusion criteria

Exclusion criteria: Subjects were excluded from this study if there is distant metastasis, or the duration of operation was less than 2 h, or the patient has a history of radiation and chemotherapy, or the immune system disease, or existing spinal canal anesthesia contraindications, or allogeneic blood is used during the operation, low temperature (lower than 34 degree C), the halide allergies.

Design outcomes

Primary

MeasureTime frame
natural killer cell;TH1 / TH2;cortisol;

Secondary

MeasureTime frame
VAS score;

Countries

China

Contacts

Public ContactYunlong Zhang

Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College

502450440@qq.com+86 13706512628

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026