Tuberculosis
Conditions
Interventions
Control group:no L.casei
Low dose group:10 billion L.casei strains
Medium dose group:20 billion L.casei strains
High dose group:30 billion L.casei strains
Sponsors
Linyi City People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years old; 2. Early treatment and rehabilitation of tuberculosis patients; 3. Have not taken with probiotics (such as lactic acid bacteria, bifidobacteria, etc.) yogurt, beverages and etc In the past two months; 4. Can adhere to the requirements of taking L.casei for 2 months; 5. Cooperate with the survey And the collection of blood samples, feces and other biological samples; 6. Volunteers who sign the informed consent.;Inclusion criteria: 1. Aged 18 to 65 years old; 2. Early treatment and rehabilitation of tuberculosis patients; 3. Have not taken with probiotics (such as lactic acid bacteria, bifidobacteria, etc.) yogurt, beverages and etc In the past two months; 4. Can adhere to the requirements of taking L.casei for 2 months; 5. Cooperate with the survey And the collection of blood samples, feces and other biological samples; 6. Volunteers who sign the informed consent.;Inclusion criteria: 1. Aged 18 to 65 years old; 2. Early treatment and rehabilitation of tuberculosis patients; 3. Have not taken with probiotics (such as lactic acid bacteria, bifidobacteria, etc.) yogurt, beverages and etc In the past two months; 4. Can adhere to the requirements of taking L.casei for 2 months; 5. Cooperate with the survey And the collection of blood samples, feces and other biological samples; 6. Volunteers who sign the informed consent.;Inclusion criteria: 1. Aged 18 to 65 years old; 2. Early treatment and rehabilitation of tuberculosis patients; 3. Have not taken with probiotics (such as lactic acid bacteria, bifidobacteria, etc.) yogurt, beverages and etc In the past two months; 4. Can adhere to the requirements of taking L.casei for 2 months; 5. Cooperate with the survey And the collection of blood samples, feces and other biological samples; 6. Volunteers who sign the informed consent.;Inclusion criteria: 1. Aged 18 to 65 years old; 2. Early treatment and rehabilitation of tuberculosis patients; 3. Have not taken with probiotics (such as lactic acid bacteria, bifidobacteria, etc.) yogurt, beverages and etc In the past two months; 4. Can adhere to the requirements of taking L.casei for 2 months; 5. Cooperate with the survey And the collection of blood samples, feces and other biological samples; 6. Volunteers who sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. pregnant or lactating women; 2. extrapulmonary tuberculosis such as intestinal tuberculosis, bone tuberculosis, etc; 3. accompanied by diabetes, cardiovascular and cerebrovascular diseases, liver (such as liver cancer, hepatitis B, etc.), hematopoietic system diseases; Enteritis, etc; 4. accompanied by mental illness.;Exclusion criteria: 1. pregnant or lactating women; 2. extrapulmonary tuberculosis such as intestinal tuberculosis, bone tuberculosis, etc; 3. accompanied by diabetes, cardiovascular and cerebrovascular diseases, liver (such as liver cancer, hepatitis B, etc.), hematopoietic system diseases; Enteritis, etc; 4. accompanied by mental illness.;Exclusion criteria: 1. pregnant or lactating women; 2. extrapulmonary tuberculosis such as intestinal tuberculosis, bone tuberculosis, etc; 3. accompanied by diabetes, cardiovascular and cerebrovascular diseases, liver (such as liver cancer, hepatitis B, etc.), hematopoietic system diseases; Enteritis, etc; 4. accompanied by mental illness.;Exclusion criteria: 1. pregnant or lactating women; 2. extrapulmonary tuberculosis such as intestinal tuberculosis, bone tuberculosis, etc; 3. accompanied by diabetes, cardiovascular and cerebrovascular diseases, liver (such as liver cancer, hepatitis B, etc.), hematopoietic system diseases; Enteritis, etc; 4. accompanied by mental illness.;Exclusion criteria: 1. pregnant or lactating women; 2. extrapulmonary tuberculosis such as intestinal tuberculosis, bone tuberculosis, etc; 3. accompanied by diabetes, cardiovascular and cerebrovascular diseases, liver (such as liver cancer, hepatitis B, etc.), hematopoietic system diseases; Enteritis, etc; 4. accompanied by mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| height;weight;Waist circumference;Hip circumference;Fecal flora genomics;Fecal flora;Blood routine;Fecal routine;Blood lipids;liver function;Renal function; | — |
Countries
China
Contacts
Public ContactAiguo Ma;Aiguo Ma;Aiguo Ma;Aiguo Ma;Aiguo Ma ;;;;
Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University
Outcome results
None listed