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The study of the effect of cranberry juice on Helicobacter pylori and gastrointestinal mucosal injury

The study of the effect of cranberry juice on Helicobacter pylori and gastrointestinal mucosal injury

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013209
Enrollment
Unknown
Registered
2017-11-01
Start date
2017-11-10
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

positive H. pylori

Interventions

control group:2 servings of placebo juice per day
Low dose group:One bottle of cranberry juice per day plus 1 bottle of placebo juice
High dose group:2 bottles of cranberry juice per day

Sponsors

Affiliated Hospital of Binzhou Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 64 years old who signed informed consent, Helicobacter pylori positive by using urea breath test (UBT test); 2. Volunteers should follow established research programs to provide medical treatment history and family history; 3. Agree to accept dietary guidance, avoid eating probiotics, cranberry supplies, blueberry extract, grape seed extract and litchi and etc. (Marked in the record book issued to the study object) during the trial; 4. Have a fixed home address to be followed up.;Inclusion criteria: 1. Aged 18 to 64 years old who signed informed consent, Helicobacter pylori positive by using urea breath test (UBT test); 2. Volunteers should follow established research programs to provide medical treatment history and family history; 3. Agree to accept dietary guidance, avoid eating probiotics, cranberry supplies, blueberry extract, grape seed extract and litchi and etc. (Marked in the record book issued to the study object) during the trial; 4. Have a fixed home address to be followed up.;Inclusion criteria: 1. Aged 18 to 64 years old who signed informed consent, Helicobacter pylori positive by using urea breath test (UBT test); 2. Volunteers should follow established research programs to provide medical treatment history and family history; 3. Agree to accept dietary guidance, avoid eating probiotics, cranberry supplies, blueberry extract, grape seed extract and litchi and etc. (Marked in the record book issued to the study object) during the trial; 4. Have a fixed home address to be followed up.;Inclusion criteria: 1. Aged 18 to 64 years old who signed informed consent, Helicobacter pylori positive by using urea breath test (UBT test); 2. Volunteers should follow established research programs to provide medical treatment history and family history; 3. Agree to accept dietary guidance, avoid eating probiotics, cranberry supplies, blueberry extract, grape seed extract and litchi and etc. (Marked in the record book issued to the study object) during the trial; 4. Have a fixed home address to be followed up.;Inclusion criteria: 1. Aged 18 to 64 years old who signed informed consent, Helicobacter pylori positive by using urea breath test (UBT test); 2. Volunteers should follow established research programs to provide medical treatment history and family history; 3. Agree to accept dietary guidance, avoid eating probiotics, cranberry supplies, blueberry extract, grape seed extract and litchi and etc. (Marked in the record book issued to the study object) during the trial; 4. Have a fixed home address to be followed up.

Exclusion criteria

Exclusion criteria: 1. Subjects have a history of ulcerative disease in the digestive system; 2. Subjects who took the treatment of Helicobacter pylori antibiotics witnin 2 months; 3. Subjects who uses antibiotics or use antibiotics within 3 months; 4. pregnant, lactating and pregnant women; 5. Subjects who is allergy to cranberry; 6. Subjects who is in the treatment of unstable disease or serious health problems; 7. Subjects who is currently taking anticoagulants (warfarin, coumarin, etc.); 8. Subjects who have a history of alcohol or drug abuse in the past 6 months; 9. Cognitive impairment; 10. Researchers believe that does not meet the project requirements (such as intestinal irritation, etc.).;Exclusion criteria: 1. Subjects have a history of ulcerative disease in the digestive system; 2. Subjects who took the treatment of Helicobacter pylori antibiotics witnin 2 months; 3. Subjects who uses antibiotics or use antibiotics within 3 months; 4. pregnant, lactating and pregnant women; 5. Subjects who is allergy to cranberry; 6. Subjects who is in the treatment of unstable disease or serious health problems; 7. Subjects who is currently taking anticoagulants (warfarin, coumarin, etc.); 8. Subjects who have a history of alcohol or drug abuse in the past 6 months; 9. Cognitive impairment; 10. Researchers believe that does not meet the project requirements (such as intestinal irritation, etc.).;Exclusion criteria: 1. Subjects have a history of ulcerative disease in the digestive system; 2. Subjects who took the treatment of Helicobacter pylori antibiotics witnin 2 months; 3. Subjects who uses antibiotics or use antibiotics within 3 months; 4. pregnant, lactating and pregnant women; 5. Subjects who is allergy to cranberry; 6. Subjects who is in the treatment of unstable disease or serious health problems; 7. Subjects who is currently taking anticoagulants (warfarin, coumarin, etc.); 8. Subjects who have a history of alcohol or drug abuse in the past 6 months; 9. Cognitive impairment; 10. Researchers believe that does not meet the project requirements (such as intestinal irritation, etc.).;Exclusion criteria: 1. Subjects have a history of ulcerative disease in the digestive system; 2. Subjects who took the treatment of Helicobacter pylori antibiotics witnin 2 months; 3. Subjects who uses antibiotics or use antibiotics within 3 months; 4. pregnant, lactating and pregnant women; 5. Subjects who is allergy to cranberry; 6. Subjects who is in the treatment of unstable disease or serious health problems; 7. Subjects who is currently taking anticoagulants (warfarin, coumarin, etc.); 8. Subjects who have a history of alcohol or drug abuse in the past 6 months; 9. Cognitive impairment; 10. Researchers believe that does not meet the project requirements (such as intestinal irritation, etc.).;Exclusion criteria: 1. Subjects have a history of ulcerative disease in the digestive system; 2. Subjects who took the treatment of Helicobacter pylori antibiotics witnin 2 months; 3. Subjects who uses antibiotics or use antibiotics within 3 months; 4. pregnant, lactating and pregnant women; 5. Subjects who is allergy to cranberry; 6. Subjects who is in the treatment of unstable disease or serious health problems; 7. Subjects who is currently taking anticoagulants (warfarin, coumarin, etc.); 8. Subjects who have a history of alcohol or drug abuse in the past 6 months; 9. Cognitive impairment; 10. Researchers believe that does not meet the project requirements (such as intestinal irritation, etc.).

Design outcomes

Primary

MeasureTime frame
Carbon 13 urea breath test;gastroscope;Physical examination;Blood routine;Blood lipids;blood sugar;Immunological examination;

Countries

China

Contacts

Public ContactAiguo Ma;Aiguo Ma;Aiguo Ma;Aiguo Ma;Aiguo Ma ;;;;

Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University;Department of Nutrition and Health, Qingdao University

magfood@126.com;magfood@126.com;magfood@126.com;magfood@126.com;magfood@126.com+86 13805422696;+86 13805422696;+86 13805422696;+86 13805422696;+86 13805422696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026