Skip to content

The application of opioid-free and regular opioid inhalational-intravenous anesthesia in spinal surgery: a prospective randomised double-blind study

The application of opioid-free and regular opioid inhalational-intravenous anesthesia in spinal surgery: a prospective randomised double-blind study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013080
Enrollment
Unknown
Registered
2017-10-22
Start date
2017-11-01
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal surgery

Interventions

W: opioid-free inhalational-intravenous anesthesia
C: regular opioid inhalational-intravenous anesthesia

Sponsors

Department of Anesthesiology, Zhongshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Elective posterior right incision lumbar vertebral single or multiple decompression by intervertebral foramen fusion bone grafting; 2. Aged 18-65 years old; 3. ASA I~II; 4. Volunteered to participate in this clinical researcher.;Inclusion criteria: 1. Elective posterior right incision lumbar vertebral single or multiple decompression by intervertebral foramen fusion bone grafting; 2. Aged 18-65 years old; 3. ASA I~II; 4. Volunteered to participate in this clinical researcher.;Inclusion criteria: 1. Elective posterior right incision lumbar vertebral single or multiple decompression by intervertebral foramen fusion bone grafting; 2. Aged 18-65 years old; 3. ASA I~II; 4. Volunteered to participate in this clinical researcher.;Inclusion criteria: 1. Elective posterior right incision lumbar vertebral single or multiple decompression by intervertebral foramen fusion bone grafting; 2. Aged 18-65 years old; 3. ASA I~II; 4. Volunteered to participate in this clinical researcher.;Inclusion criteria: 1. Elective posterior right incision lumbar vertebral single or multiple decompression by intervertebral foramen fusion bone grafting; 2. Aged 18-65 years old; 3. ASA I~II; 4. Volunteered to participate in this clinical researcher.

Exclusion criteria

Exclusion criteria: 1. Liver dysfunction; 2. Renal insufficiency; 3. Diabetes; 4. Nervous system diseases; 5. Heart failure (EF <40%); 6. Uncontrolled severe hypertension (systolic blood pressure = 180mmHg, diastolic blood pressure = 110mmHg); 7. Diabetes; 8. Perioperative use of calcium channel blockers or recently taking magnesium; 9. Clear diagnosis of gastric tension, gastric motility disorders; 10. Past history of stomach surgery (stomach resection, etc.); 11. History of chronic pain, long history of drinking, history of drug abuse; 12. Pregnant women; 13. Refused to use analgesic pump patients.;Exclusion criteria: 1. Liver dysfunction; 2. Renal insufficiency; 3. Diabetes; 4. Nervous system diseases; 5. Heart failure (EF <40%); 6. Uncontrolled severe hypertension (systolic blood pressure = 180mmHg, diastolic blood pressure = 110mmHg); 7. Diabetes; 8. Perioperative use of calcium channel blockers or recently taking magnesium; 9. Clear diagnosis of gastric tension, gastric motility disorders; 10. Past history of stomach surgery (stomach resection, etc.); 11. History of chronic pain, long history of drinking, history of drug abuse; 12. Pregnant women; 13. Refused to use analgesic pump patients.;Exclusion criteria: 1. Liver dysfunction; 2. Renal insufficiency; 3. Diabetes; 4. Nervous system diseases; 5. Heart failure (EF <40%); 6. Uncontrolled severe hypertension (systolic blood pressure = 180mmHg, diastolic blood pressure = 110mmHg); 7. Diabetes; 8. Perioperative use of calcium channel blockers or recently taking magnesium; 9. Clear diagnosis of gastric tension, gastric motility disorders; 10. Past history of stomach surgery (stomach resection, etc.); 11. History of chronic pain, long history of drinking, history of drug abuse; 12. Pregnant women; 13. Refused to use analgesic pump patients.;Exclusion criteria: 1. Liver dysfunction; 2. Renal insufficiency; 3. Diabetes; 4. Nervous system diseases; 5. Heart failure (EF <40%); 6. Uncontrolled severe hypertension (systolic blood pressure = 180mmHg, diastolic blood pressure = 110mmHg); 7. Diabetes; 8. Perioperative use of calcium channel blockers or recently taking magnesium; 9. Clear diagnosis of gastric tension, gastric motility disorders; 10. Past history of stomach surgery (stomach resection, etc.); 11. History of chronic pain, long history of drinking, history of drug abuse; 12. Pregnant women; 13. Refused to use analgesic pump patients.;Exclusion criteria: 1. Liver dysfunction; 2. Renal insufficiency; 3. Diabetes; 4. Nervous system diseases; 5. Heart failure (EF <40%); 6. Uncontrolled severe hypertension (systolic blood pressure = 180mmHg, diastolic blood pressure = 110mmHg); 7. Diabetes; 8. Perioperative use of calcium channel blockers or recently taking magnesium; 9. Clear diagnosis of gastric tension, gastric motility disorders; 10. Past history of stomach surgery (stomach resection, etc.); 11. History of chronic pain, long history of drinking, history of drug abuse; 12. Pregnant women; 13. Refused to use analgesic pump patients.

Design outcomes

Primary

MeasureTime frame
Emptying speed of stomach;Pain evaluation;Consumption of Sufentanil post surgery;

Secondary

MeasureTime frame
nausea and vomiting postoperative;the first exhaust time;

Countries

China

Contacts

Public ContactJing Cang;Jing Cang;Jing Cang;Jing Cang;Jing Cang ;;;;

Department of Anesthesiology, Zhongshan Hospital ;Department of Anesthesiology, Zhongshan Hospital ;Department of Anesthesiology, Zhongshan Hospital ;Department of Anesthesiology, Zhongshan Hospital ;Department of Anesthesiology, Zhongshan Hospital

cang.jing@zs-hospital.sh.cn;cang.jing@zs-hospital.sh.cn;cang.jing@zs-hospital.sh.cn;cang.jing@zs-hospital.sh.cn;cang.jing@zs-hospital.sh.cn+86 13916010421;+86 13916010421;+86 13916010421;+86 13916010421;+86 13916010421

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026