alveolar bone defect
Conditions
Interventions
test group:Heal-All bone repair material
Control group:Bio-Oss
Sponsors
Hospital of Stomatology of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1) with both sides of the jaw are required to remove the posterior teeth (molar or premolars), and the need for line repair patients; 2) Alveolar fossa at least three walls, and any side of the bone wall defects do not exceed two-thirds; 3) after tooth extraction with periodontal probe to measure the depth of alveolar fossa = 6 mm; 4) patients with good oral environment, good compliance; 5) Aged 18-55 years male and female; 6) Patients who voluntarily participate in and sign "informed consent" after obtaining full knowledge.
Exclusion criteria
Exclusion criteria: 1) have serious heart, liver, lung, kidney and other vital organs or severe blood, immune, endocrine (such as: uncontrollable diabetes) and other systemic diseases; 2) A history of chronic disease treatment known to affect oral environmental drugs (eg phenytoin, dihydropyridine calcium antagonists, cyclosporine, nonsteroidal anti-inflammatory drugs) within 1 month prior to enrollment (= 2 weeks); 3) suffering from bone metabolic diseases (such as: osteoporosis, deformed osteitis, etc.), or within 1 month before taking the drug can significantly affect the bone metabolism of drugs or products (such as steroids, bisphosphonates); 4) 6 months before enrollment with severe smoking history (> 10 / day); 5) alcohol or long-term drug abusers; 6) pregnant or lactating women; 7) allergic constitution, with collagen allergy or other serious allergic reactions past history; 8) have mental illness or mental disorders; 9) severe periodontal disease, and can not be effective control; 10) oral inflammation, infection can not control; 11) history of head and neck radiotherapy; 12) Other patients who have been judged by the investigator who are not eligible for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Micro-CT observation and analysis of indicators;Histological observation and analysis of indicators;CBCT observation of bone mass analysis of indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Implant stability analysis index;Clinical observation; | — |
Countries
China
Contacts
Public ContactBin Shi
Outcome results
None listed