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Effects of different doses of atorvastatin calcium on vascular endothelial time and repair ability and time in patients with coronary heart disease

Effects of different doses of atorvastatin calcium on vascular endothelial time and repair ability and time in patients with coronary heart disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17013026
Enrollment
Unknown
Registered
2017-10-18
Start date
2014-01-01
Completion date
Unknown
Last updated
2017-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

40 mg group:before treatment, 5th, 15th, 20th, 30th, 60th, 90th and 120th days after treatment
20 mg group:before treatment, 5th, 15th, 20th, 30th, 60th, 90th and 120th days after treatment

Sponsors

Vasculocardiology Department, Liuzhou People's Hospital, Liuzhou, Guangxi
Lead Sponsor

Eligibility

Sex/Gender
All
Age
34 Years to 82 Years

Inclusion criteria

Inclusion criteria: Diagnosed with coronary heart disease, never used statins of the crowd.

Exclusion criteria

Exclusion criteria: (1) The patient with persistent or elevated levels of transaminases; (2) The patient with severe creatine phosphokinase during the course of administration and accompanied by myositis and pancreatitis; (3) During the course of administration; (4) The patient with renal insufficiency caused by rhabdomyolysis; (5) The patient with atorvastatin calcium calcium allergy; (6) pregnant women and maternal.

Design outcomes

Primary

MeasureTime frame
CD34;CD133;KDR;C-X-C chemokine receptor type 4,CXCR4;vascular endothelial growth factor,VEGF;basic fibroblast growth factor , bFGF;Silent mating type information regulation 2 homolog- 1 Sirtuin type 1, Sirt1;

Countries

China

Contacts

Public ContactJie Liu

Vasculocardiology Department, Liuzhou People's Hospital, Liuzhou, Guangxi

ljlzx153019@163.com+86 13507729218

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026