Postoperative pain
Conditions
Interventions
single-shot ACB group:single-shot adductor canal block group with ropivacaine 0.5 %, 20ml preoperatively
continuous ACB group:continuous adductor canal block with ropivacaine 0.5 %, 20ml preoperatively, 12h and 24h postoperatively
Control group:saline preoperatively and postoperatively
Sponsors
Department of Anesthesiology, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Eligibility criteria included patients have ability to follow study protocol, be scheduled for elective unilateral primary TKA, aged 18 to 90 years, body mass index 18 to 40 kg/m2, and American Society of Anesthesiologists class 1 to 3.
Exclusion criteria
Exclusion criteria: 1. Chronic opioid use (defined as daily or almost daily use of opioids for >3 months); 2. Alcohol or drug abuse, hypersensitivity or allergies to any of the study medications(local anesthetics); 3. Preexisting neuropathy or trauma/surgical history on the operative limb; 4. Diabetes mellitus combined with peripheral neuropathy; 5. Blocks are void in 20 minutes(pain threshold measured by Von Frey Filaments rises less than 40%); 6. Patients for various reasons can not follow study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the differences of dynamic VAS pain scores on postoperative day 1; | — |
Countries
China
Contacts
Public ContactJing Yang
West China Hospital, Sichuan University
Outcome results
None listed