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Efficacy of prophylactic intravesical chemotherapy for bladder tumor recurrence after radical nephroureterectomy for upper tract urothelial carcinoma: a multicenter, prospective, randomized study

Efficacy of prophylactic intravesical chemotherapy for bladder tumor recurrence after radical nephroureterectomy for upper tract urothelial carcinoma: a multicenter, prospective, randomized study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17012952
Enrollment
Unknown
Registered
2017-10-12
Start date
2017-10-16
Completion date
Unknown
Last updated
2017-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

UTUC

Interventions

multiple-instillation group:Pirarubicin 30mg after RNU for 6 times
single-instillation group:Pirarubicin 30mg after RNU only once

Sponsors

the First Affiliated Hospital, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. unilateral UTUC; 2. radical nephroureterectomy with cuff of the bladder; 3. patholgy was urothelial carcinoma; 4. No distant metastasis.

Exclusion criteria

Exclusion criteria: 1. Distant metastasis; 2. Concomitant with bladder cancer; 3. Previous urothelial carcinoma history; 4. Preoperatively receiving neoadjuvant chemotherapy;

Design outcomes

Primary

MeasureTime frame
Bladder tumor recurrence;—

Secondary

MeasureTime frame
tumor progression;local recurrence;durg adverse effect;overall survival;—

Countries

China

Contacts

Public ContactWei Chen

the First Affiliated Hospital, Sun Yat-sen University

chenweisysuuro@163.com+86 020-87755766-8227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026