Epidermal Pigmentation
Conditions
Interventions
Control Group:Q-Switched Alexandrite Laser
Experimental Group:Alexandrite Laser
Sponsors
Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical Collage
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Female or male between 18-65 years-old; 2. Presents with epidermal pigmented lesions, i.e. Freckles that without receiving any type of procedures. 3. Fitzpatrick skintypes III~V; 4. Subjects who understand/accept obligation not to receive any other procedures in facial area through the length of the study; 5. Subjects who understand and accept the obligation and is logistically able to present for all scheduled follow-up visits; 6. Subjects who are willing to sign the informed consent form and participate this study voluntarily.
Exclusion criteria
Exclusion criteria: 1. The subject has scar or mark on the treatment area which may affect the evaluation of outcome; 2. The subject has dermatologic diseases or infections on face; 3. The subject is hypersensitive to light exposure OR takes photo sensitized medication; 4. The subject had excessive sunlight expose over the last 6 months; 5. The subject has taken oral vitamin A drug medicine during the last 6 months; 6. The subject has a coagulation disorder or is currently using anti-coagulation medication (including but not limited to heavy aspirin therapy); 7. The subject has a history of immunosuppression/immune deficiency disorders (including HIV infection or AIDS) or use of immunosuppressive medications; 8. The subject has a history of keloids; 9. The subject has a history of side effect to Propylamine cocaine or lidocaine products; 10. The subject has serious cardiovascular, gastrointestinal, respiratory, endocrine or central nervous system disorders and psychiatric disorders that may have adverse effects on this clinical trial; 11. The subject was enrolled in other clinical trials 30 days prior to the screening day or was enrolled to other clinical cosmetic study within 6 months cant be enrolled to this study; 12. Is pregnant or currently breast feeding; 13. The subject who does not agree to apply medically effective birth control (Medical acceptable contraceptive methods: use of condoms, oral contraceptives for more than 3 months of continuous use, injection or implantation of contraceptives, placement of IUD (IUD); 14. Any medical condition that, in the investigators opinion would interfere with the patients participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete treated rate;GAIS score;Pain scale;Satisfaction rate; | — |
Countries
China
Contacts
Public ContactTong Lin
Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical Collage
Outcome results
None listed