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Intermittent vs continuous proton pump inhibitor for artificial ulcer after ESD operation of gastric mucosa-multi-center randomized controlled clinical trials

Intermittent vs continuous proton pump inhibitor for artificial ulcer after ESD operation of gastric mucosa-multi-center randomized controlled clinical trials

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17012738
Enrollment
Unknown
Registered
2017-09-19
Start date
2017-09-01
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early gastric cance

Interventions

experimental group:Nexium 40mg bid* 72h
control group:Nexium 80-mg intravenous bolus followed by an 8-mg infusion per hour

Sponsors

Xinqiao Hospital of Third Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. aged from 18 to 70 years; 2. inpatient,male or female; 3. patients diagnosed with mucosal lesions (early gastric cancer or gastric adenoma); 4. patients conform to operation indications and complete ESD surgery; 5. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and breastfeeding women; 2. patients with severe cardiovascular disease,hemorrhagic disease,abnormal liver function and abnormal rennal function; 3. patients with mental illness; 4. patients taking drugs which affected the coagulation function; 5. patients participated in the other drug research three months ago; 6. patients were allergic to research drug; 7. refused to sign a consent form.

Design outcomes

Primary

MeasureTime frame
rebleeding rate;endoscopic treatment;surgical treatment;

Secondary

MeasureTime frame
hospitalization costs;length of hospital stay;

Countries

China

Contacts

Public ContactShiming Yang

Xinqiao Hospital of Third Military Medical University

shimingyang@yahoo.com+86 13228686589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026