Rectal cancer
Conditions
Interventions
aspirin group:perioperative continuous use of aspirin
non-aspirin group:discontinuous use of aspirin for 7 days before operation
Sponsors
Department of Colorectal Surgery, Shengjing Hospital, China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) aged = 18 years old male and female; (2) patients diagnosed as rectal cancer by preoperative colonoscopy biopsy.cancer. elective laparoscopic anterior resection for rectal cancer; (3) The treatment duration of oral aspirin (75 ~ 100 mg / d) is more than 6 months; (4) the number of preoperative PLT and coagulation function are normal; (5) voluntarily join the study.
Exclusion criteria
Exclusion criteria: (1) The tumor diameter was more than 4cm.Tumor stage> T3 or lymph node metastasis positive need new adjuvant therapy. (2) Tumor distant metastasis confirmed by preoperative CT or MIR examinatio; (3) previous history of larger abdominal surgery; (4) Combined with blood system diseases; (5) Taking other anticoagulant or anti-PLT drugs; (6) The patients did not take aspirin as require; (7) American Association of Anesthesiologists (ASA) grade IV-V; (8) postoperative need for intensive care.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| conversion to open surgery rate;operative time;duration before first flatus;postoperative drainage volume;rate of total postoperative complications;rate of intraoperative complication;length of postoperative hospital stay;overall hospital costs;postoperative TNM stage;Postoperative coagulation index; | — |
Primary
| Measure | Time frame |
|---|---|
| blood loss;postoperative hemoglobin decreased amount;postoperative hematochezia rate; major thromboembolic events rate; | — |
Countries
China
Contacts
Public ContactHong Zhang
Department of Colorectal Surgery, Shengjing Hospital, China Medical University
Outcome results
None listed