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Effect of dexmedetomidine on liver injury in adults undergoing colon cancer surgery

Effect of dexmedetomidine on liver injury in adults undergoing colon cancer surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17012707
Enrollment
Unknown
Registered
2017-09-18
Start date
2017-10-31
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colon cancer surgery

Interventions

Dexmedetomidine group:continuous infusion of 1 µg/kg dexmedetomidine (4 µg/ml) for 20 min
Control group:Infusion of saline of the same volume

Sponsors

Dept. of Anesthesiology,The Affliliated Hospital Of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients undergoing elective colon cancer surgery, aged more than 18 years old, ASA I~II level, signed informed consent.

Exclusion criteria

Exclusion criteria: patients with a history of cardiac, respiratory, renal or hepatic disease, psychological disorders, allergy to study medications, and any other contraindication for general anesthesia.

Design outcomes

Primary

MeasureTime frame
AST, ALT, bilirubin, INR, serum lactate, and serum creatinine values;—

Secondary

MeasureTime frame
length of hospital stay;—

Countries

China

Contacts

Public ContactShuai Miao

Affiliated Hospital of Xuzhou Medical University

843916335@qq.com+86 18752113527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026