Diabetic kidney disease
Conditions
Interventions
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Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Being diagnosed diabetic kidney disease and meet the criteria for the staging of DKD renal failure in the subject; 2. Aged 25 to 65 years, male or female; 3. Have not received dialysis treatment; 4. Scr was relatively stable in 3 months ago for people who are chosen, with no change of over 15%; 5. for those with hypertesion, blood pressure should be control to less than 140/90mmHg, for people over 60 years old, the SBP should be less than150mmHg;Glycated hemoglobin (HbA1c) should be less than 7.0%; 6. HGB is at least higher than 110g/L (or by conventional Western Medicine treatment, HGB =110g/L); 7. subjects must be informed details of the trail and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Have severe infection or anemia, or electrolyte disorders, acute complications of diabetes in recent 4 weeks; 2. Have had serious heart, brain, liver or hemorrhage disease (like cerebral infarction, cerebral hemorrhage, transient ischemic attack, myocardial infarction, unstable angina, heart failureor result of ALT or AST is higher than 2 times of normal range and those who have been treated with corticosteroids or immunosuppressants in recent 3 month; 3. oliguria or anuria, severe edema, massive pleural and peritoneal effusion; 4. Have received renal transplantation; 5. Subjest with mental illness; 6. Women in gestational lactational period; 7. Allergic to the trial drugs; 8. Hepatitis B surface antigen positive; 9. Being enrolled to other clinical study; 10. not fully understand, reluctant to participant in, or do not sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urinary protein quantity;Scr;eGFR; | — |
Secondary
| Measure | Time frame |
|---|---|
| HGB;ALB;TCM syndrome;Quality of life; | — |
Countries
China
Contacts
Public ContactYaoxian Wang
Dongzhimen Hospital, Beijing University of Chinese Medicine
Outcome results
None listed