Lung cancer
Conditions
Interventions
Group L:lidocaine
Group C:Placebo (N.S.)
Sponsors
Department of Anesthesiology; Chongqing Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years male and female, the thoracoscope surgery in patients with lung cancer; 2. ASA I - III level; 3. No serious viscera lesions and poorly controlled system disease; 4. The preoperative pulmonary function normal or the existence of mild-to-moderate ventilation dysfunction and FEV1 / FVC % > 50%, PaO2 > 60 MMHG; 5. Preoperative visit MMSE score 24 points or more; 6. Get informed consent.
Exclusion criteria
Exclusion criteria: 1. Confirmed by preoperative pulmonary CT exist atelectasis, pulmonary emphysema, pulmonary interstitial changes such as the lungs (except tumor local change); 2. The preoperative have not controlling pulmonary infection, tuberculosis, without or did not complete the chemotherapy treatment, severe and very severe obstructive pulmonary disease (copd), asthma; 3. The preoperative nerve mental illness, liver and kidney function is not complete; 4. Before the WBC 10 x10^9/L; 5. Preoperative with chronic pain; 6. Preoperative pain relievers used within seven days, including the opioid and non opioid; 7. Before the surgery has a history of drug or alcohol abuse; 8. Lidocaine anesthesia drug allergy, etc.; 9. Preoperative ecg or dynamic electrocardiogram indicates a conduction block, sinus arrest, atrial flutter, and other serious arrhythmia, etc.; 10. A variety of reasons lead to not plan early extubation; 11. Cases for other reasons need to transit thoracotomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| major adverse cardiac events;Postoperative delirium;intraoperative lung function;PONV; | — |
Countries
China
Contacts
Public ContactLIU HONGLIANG
Chongqing Cancer Institute & Hospital & Cancer Center
Outcome results
None listed