knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) aged 38 to 70 years; (2) meet the diagnostic criteria of primary knee osteoarthritis; (3) drug (non-steroidal anti-inflammatory drugs, pain relievers, traditional Chinese medicine and Chinese patent medicine) for knee osteoarthritis elution after 7 days, WOMAC96 joint index scores between > 48 to 72 or less, the grading for moderate to severe knee osteoarthritis disease; (4) the Kellgren and Lawrecne osteoarthritis class for II or III radiology.
Exclusion criteria
Exclusion criteria: (1) non-primary knee osteoarthritis (such as secondary knee osteoarthritis; Inflammatory or other rheumatic diseases; Symptomatic hip arthritis or patella osteoarthritis in the same side of the target knee (2) the target knee injury in nearly a year (such as acute injury of knee joint meniscus, or acute knee ligament damage/around fracture, etc.) or a history of surgery, or severe joint deformities (varus or valgus 8 degree or higher); Or peripheral tumor, tuberculosis or idiopathic bone necrosis; (3) the target knee joint was injected with glucocorticoid in the joint cavity for nearly three months, or injection of sodium hyaluronate in the joint cavity within 2 weeks; (4) patients with acetaminophen, non-steroidal anti-inflammatory drugs or analgesics for other diseases; (5) uncontrolled hypertension or diabetes, severe cardiovascular and cerebrovascular, pulmonary, liver, spleen, kidney and hematopoietic system disease, tumor, hemorrhagic disease and mental illness; (6) scar or skin sensation; (7) pregnant or lactating women; (8) refusal to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC osteoarthritis index pain project score;visual analogue scale, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC osteoarthritis index score, rigid project score and joint function project score;Overall assessment of patients; | — |
Countries
China
Contacts
Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences