aerobic vaginitis combined with bacterial vaginosis
Conditions
Interventions
Sophora flavescens alkaloid gels treatment group:Sophora flavescens alkaloid gelsVaginal placement
Metronidazole treatment group:Metronidazole oral
Sophora flavescens alkaloid gels treatment group combine Metronidazole treatment group:Sophora flavescens alkaloid gels treatment group combine Metronidazole treatment
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients with AV combined with BV confirmed by clinical and laboratory pathogenic examination before the test; 2. With follow-up conditions, good compliance and signed informed consent of volunteers; 3. 18-50 years of age with sexual life history, menstrual period; 4. Patients who were not treated with any oral medication in the last one month; 5. Patients who were not treated with any external drugs in the last two weeks; 6. The pregnancy test was negative in women of childbearing age, during the test can adhere to contraception and condom use in life.
Exclusion criteria
Exclusion criteria: 1. Those with fungal, viral or other microbial infections; severe cervical erosion; 2. Other diseases need to be treated with antibiotics, hormones, immunosuppressive drugs and other drugs; 3. HIV positive or abnormal immune function; 4. Patients with poorly controlled diabetes; 5. Severe liver and kidney dysfunction; combined with heart disease such as congestive heart failure, malignant arrhythmia, etc.; 6. During the test the other operation plan; 7. Pregnant and lactating women, and planned pregnancy within 3 months; 8. Allergic, or allergic to this test drug; 9. Other clinical trials in last one month; 10. Unconditional follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AV score was evaluated by wet film microscopy;Nufent score was evaluated by dry slice microscopy;Evaluation of clinical efficacy based on symptoms and signs;Onset time;Recurrence rate; | — |
Countries
China
Contacts
Public ContactFengxia Xue
Tianjin Medical University General Hospital
Outcome results
None listed