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Can sevoflurane preconditioning be protective to endothelial surface layer of lung vessles during off-pump coronary artery bypass surgery

Can sevoflurane preconditioning be protective to endothelial surface layer of lung vessles during off-pump coronary artery bypass surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17012535
Enrollment
Unknown
Registered
2017-09-01
Start date
2017-09-06
Completion date
Unknown
Last updated
2017-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative lung injury

Interventions

preconditioning group:sevoflurane preconditioning
control group:anesthesia maintained by propofol

Sponsors

Beijing Chaoyang Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. patients undergoing elective OPCABG surgery; 2. ASA III; 3. BMI 18.5-30; 4. voluntary participation.

Exclusion criteria

Exclusion criteria: 1. Alcohol or substance abuse; 2. abnormal renal function SCr >1.2mg/dl; 3. Acute myocardial infarction; 4. Uncontrolled diabetes.

Design outcomes

Primary

MeasureTime frame
Syndecan-1;atrial natriuretic peptide ANP;brain natriuretic peptide BNP;heparan sulfate HS;serum albumin;HGB;—

Countries

China

Contacts

Public ContactWu Yan

Beijing Chaoyang Hospital Affiliated to Capital Medical University

yhanwu@sina.com+86 13651077828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026