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Application of two different doses of tranexamic acid in cardiac surgery

Application of two different doses of tranexamic acid in cardiac surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17012425
Enrollment
Unknown
Registered
2017-08-21
Start date
2017-08-01
Completion date
Unknown
Last updated
2017-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart disease

Interventions

Group 1:tranexamic acid
Group 2:0.9% saline

Sponsors

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Heart surgery patients; 2. Age <65years male and female; 3. ASA grade 2-3, cardiac function grade 2-3; 4. No serious liver and kidney function damage; 5. No history of severe allergies; 6. No preoperative convulsion history

Exclusion criteria

Exclusion criteria: 1. Secondary and multiple cardiac surgery; 2. EF% <40%; 3. Severe liver and kidney dysfunction; 4. Preoperative clotting function is abnormal; 5. Preoperative 7d aspirin clopidogrel treatment; 6. Known to tranexamic acid allergy.

Design outcomes

Primary

MeasureTime frame
Hemoglobin;—

Countries

China

Contacts

Public ContactLijian Chen

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University

chenlijian77@126.com+86 13966699467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026