chronic obstructive pulmonary disease
Conditions
Interventions
Experimenta:Tiotropium
Active Comparator:Formoterol
Sponsors
Huashan hospital, Fudan university
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged 18 to 80 years; Group A/B stable COPD according to the new GOLD2017 criteria; Patients must be able to understand and be willing to sign a written informed consent document.
Exclusion criteria
Exclusion criteria: 1. Acute exacerbation of COPD within one month prior to study entry; 2. Patients with significant diseases other than COPD; 3. A diagnosis of asthma, cystic fibrosis, bronchiectasis, or other lung diseases; 4. Patients with tachyarrhythmia or other serious heart diseases; 5. Patients with serious liver diseases; 6. Patients with serious kidney diseases; 7. Patients with serious hematological diseases; 8. Patients with other serious illnesses; 9. Patients with mental illnesses; 10. Patients with acute gastrointestinal hemorrhage within three month prior to study entry; 11. Patients with glaucoma; 12. Women in gestational and lactational period; 13. Patients participated in other clinical trials within three month prior to study entry; 14. Allergies or multiple drug allergies; 15. The staff and their family members in Huashan hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a post-bronchodilator forced expiratory volume in one second; | — |
Secondary
| Measure | Time frame |
|---|---|
| the frequency of COPD exacerbation;other lung function parameters(%FEV1, FEV1/FVC);Clinical COPD Questionnaire score;modified Medical Research Council score;COPD Assessment Test score; | — |
Countries
China
Contacts
Public ContactShengqing Li
Huashan hospital, Fudan university
Outcome results
None listed