Mental disease
Conditions
Interventions
DEX Group:0.5ug/Kg dexmedetomidine
CON Group:Saline
Sponsors
Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
16 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Patients anticipated the research and signed the informed consent voluntarily; 2. Patients treated in our hospital with depression, schizophrenia and bipolar disorder and underwent MECT for the first time; 3. From 16-55 years old male and female; 4. Patients without any psychotic drugs before MECT; 5. Patients were not included in other trials in the past three months.
Exclusion criteria
Exclusion criteria: 1. Patients refused to anticipate; 2. Patients suffered from the serious diseases of important organs, including liver and kidney dysfunction, brain organic disease, NYHA>=III dysfunction of blood coagulation, sick sinus syndrome, bradycardia(HR<55bpm), atrioventricular block of degree II and III; 3. Dexmedetomidine contraindication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PECTD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score for WMS-RC scale;Seizure duration;hemodynamics; | — |
Countries
China
Contacts
Public ContactXiang Li
Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed