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A randomized controlled study about the effect and safty of Dexamethasone and Dexmedetomidine added to ropivacaine in intercostals blockade for postoperative analgesia in thoracoscopic surgery

A randomized controlled study about the effect and safty of Dexamethasone and Dexmedetomidine added to ropivacaine in intercostals blockade for postoperative analgesia in thoracoscopic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17012183
Enrollment
Unknown
Registered
2017-07-30
Start date
2017-08-01
Completion date
Unknown
Last updated
2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia of thoracoscopy

Interventions

C1:At the end of the operation, intercostal nerve block was performed with 0.5% ropivacaine and 10mg dexamethasone
C2:At the end of the operation, intercostal nerve block was performed with 0.5% ropivacaine and Dexmedetomidine 1ug/kg
C3:At the end of the operation, intercostal nerve block was performed with 0.5% ropivacaine and 10mg dexamethasone and Dexmedetomidine 1ug/kg
A:At the end of the operation, intercostal nerve block was performed with 0.5% ropivacaine

Sponsors

The First Affiliated Hospital with Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologists(ASA)physical status I-II, aged 18-65yr, and scheduled for unilateral thoracoscopic surgery.

Exclusion criteria

Exclusion criteria: Patient with hypohepatia,renal insufficiency,severe heart or lung disease, sereve arrhythmia,drug allery (amide local anesthetic, hormone, dexmedetomidine), chroinc sedative use, chronic analgesic use, chronic systemic corticosteroid use,chronic pain syndrome, Pleural lesion, history of thoracic surgery, consciousness disorder or unable to understand the visual analogue scale(VAS), with contraindications to intercostal nerve block (such coagulopathy,anatomic variation, local anesthetic allergy) and patient refusal.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
Ramsay score;The first compression time of the analgesic pump;

Countries

China

Contacts

Public ContactCunming Liu

The First Affiliated Hospital with Nanjing Medical University

1335587409@qq.com+86 13951890866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 20, 2026