Breast Cancer
Conditions
Interventions
control :Tamoxifen + placebo group
experimental group:Tamoxifen + Yu Chai Decoction
Sponsors
Affiliated Nanhua hospital, University of South China
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged 18-80 years old; estrogen receptor-positive advanced breast cancer patients; there are lesions that can be clinically detected; tolerant tamoxifen and Yu Chai decoction long-term treatment; agreed to participate in clinical trials; to complete the extraction of peripheral blood and successful detection of ctDNA MTDH.
Exclusion criteria
Exclusion criteria: No disease progression; estrogen receptor-negative advanced breast cancer patients; do not accept or can not tolerate tamoxifen long-term treatment; do not agree to participate in clinical trials; can not complete the peripheral blood extraction or can not detect ctDNA MTDH.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effective rate;Disease progression free survival;Overall survival;peripheral blood ctDNA MTDH; | — |
Secondary
| Measure | Time frame |
|---|---|
| tissue pathology;physical examination;breast ultrasound;head, chest and abdomen enhanced CT;bone ECT scan;tumor standard test: CA125, CA153, CEA;head MRI; | — |
Countries
China
Contacts
Public ContactSong Wang
Affiliated Nanhua hospital, University of South China
Outcome results
None listed