anal fistula
Conditions
Interventions
treatment group:FiLaC combing with QingRe-Lishi Recipe
control group:anal fistulectomy+seton combing withQingRe-Lishi Recipe
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of T.C.M
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) imaging examination (nuclear magnetic resonance) in patients with complex II-IV type Parks complicated anal fistula; (2) the fistula was in stable phase and had not received any specialized instruments and surgical treatment in the past 3 months; (3) there was no operation contraindication; (4) TCM syndrome differentiation belongs to damp heat bet type; (5) Aged 18 years to 65 years old; (6) subjects without major organ dysfunction, blood routine, liver and kidney of normal cardiac function: hemoglobin is larger than 120g/L, the absolute neutrophil count (ANC) = 1.5 x 10^9/L = 80 * 10^9/, platelet L, bilirubin = 1.5ULN, alkaline phosphatase (AP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is less than 2.5 * ULN. INR = 1.5, 1.5ULN = creatinine; (7) voluntarily joined the experiment and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) colonoscopy excluded other anorectal diseases or surgical patients (including colorectal cancer, Krohn's disease, ulcerative colitis, intestinal tuberculosis, etc.); (2) hematopoietic and coagulopathy; (3) the history of cardiovascular disease: congestive heart failure > NYHA, II in heart function. Patients with unstable angina pectoris (angina pectoris at rest) or new onset angina pectoris (which started in the past 3 months) or myocardial infarction occurred in the past 6 months. Active infection, grade >2 adverse events (CTC, AE.3.0). Preoperative blood pressure was over 160/90mmHg; (4) pregnant or lactating patients; menstrual patients; (5) suffering from a history of mental illness that is difficult to control.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| curative ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of surgery;hemorrhage during surgery;Fecal incontinence severity index;Anorectal Manometry;wound healing time;visual analogue scale; | — |
Countries
China
Contacts
Public ContactZhenyi Wang
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of T.C.M
Outcome results
None listed