atopic dermatitis
Conditions
Interventions
active group:HDM oral immunotherapy
placebo group:oral placebo
Sponsors
Shanghai Jiaotong University, School of medecine, Xinhua hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. neonate participants aged 0 to 7 days; 2. high risk of atopy based on heredity: mother or siblings with moderate to severe atopic dermatitis or asthma,HDM sensitization not concerned; 3. participants with apgar score at 10 and vaccination of BCG vaccine and Hepatitis B vaccine; 4. Vital signs stable; 5. participant's parents provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. infants who were born premature(<37 weeks gestation); 2. Birth weight <2500g; 3. experience of immediate cow's milk protein allergy; 4. infant with intestinal symptoms, such as hematochezia; 5. infant with congenital hemangioma treated by oral propranolol; 6. infant with other major health problems, such as congenital heart disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative prevalence of atopic dermatitis in the end of treatment; | — |
Countries
China
Contacts
Public ContactYAO ZHIRONG
Shanghai Jiaotong University Affiliated Xinhua Hospital
Outcome results
None listed